T2 with FatSat
Coronal T2 SSFSE
Triglyceride fat fraction map
Figure 1. 10-year-old patient with NASH. Conventional MR images (top row) show an enlarged
liver and steatosis, but provide no quantitative information on the severity of the disease.
MR Touch (Elastogram image) and IDEAL IQ reveal a very stiff liver (red regions in liver), elevated
triglyceride fat fraction (22%), and increased T2* (R2*, 40 ms). Imaging and biopsy findings are
concordant and consistent with NASH.
Yet, many widely-used procedures
are still invasive, requiring a needle to
deliver contrast or sedation or obtain
a biopsy. There is growing awareness
that contrast, sedation, and biopsy
can have potentially dangerous side
effects to patients, add additional costs
to the procedures, and extend patient
Can MR help clinicians obtain the
information they need without the
use of a needle? In some cases,
the answer is yes.
The value of contrast media in
enhancing clinical images has long
been appreciated. Millions of contrast-
assisted imaging procedures are being
performed every year.1, 2 Every PET
and Nuclear Medicine scan, 35% of CT
studies, and 42% of all MR imaging
procedures1 performed today deploy
exogenous contrast agents that
are typically injected through an
intravascular (IV) line.
2 This adds to the
cost, duration, and complexity of the
procedure, not to mention contributes
to patient discomfort and anxiety.